Early Biological Response of an Ultra-Hydrophilic Implant Surface Activated by Salts and Dry Technology: An In-Vitro Study

The use of dental implants has grown over the years and led to higher success rates. To further enhance surgical outcomes, many research groups companies have shifted their focus surfaces roughness, wettability chemistry. In a recent study new dry salt bioactivate surface been described from chemical physical point view. aim this is evaluate osteogenic response pre-osteoblast cell lines bioactivated surface. MC3T3-E1 were cultured on SM (sandblasted dual acid-etched surface) HNS (SM with salts bioactive technology). Cell adhesion assay, proliferation assay morphology performed. Osteogenic activity was performed using Alizarin Red S alkaline phosphatase. results showed that determines slighter but significant increase in shorter time compared HNS. On contrary, long intertwining filopodia could be HNS-topography stage differentiation. nature more prone determine massive deposition calcium minerals. This first investigating role interesting dry-salts during phase healing its potential biochemical advantage validated by future animal studies rate bone implant contact early stages healing.